CultureScope

Culture profile

Staphylococcus aureus

  • First described 1884
  • Risk group 2
  • TaxID 1280
  • 294 evidence sentences
  • 81 sources
  • Literature 1952–2026

cellular organisms; Bacteria; Bacillati; Bacillota; Bacilli; Caryophanales; Staphylococcaceae; Staphylococcus

unreviewed

Built 12 Aug 2026 · today

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At a glance

Evidence base by publication year

How current the underlying literature is. Recent work is weighted more heavily, but classical descriptions still count — that is often where the phenotype was characterised properly.

1969 — 1 source1991 — 1 source1992 — 1 source1994 — 1 source1995 — 1 source1996 — 1 source1999 — 1 source2000 — 2 sources2004 — 1 source2005 — 1 source2006 — 3 sources2010 — 2 sources2014 — 2 sources2015 — 2 sources2016 — 2 sources2018 — 3 sources2019 — 3 sources2020 — 3 sources2021 — 5 sources2022 — 3 sources2023 — 7 sources2024 — 6 sources2025 — 7 sources2026 — 18 sources196620222026

Latest literature

The newest publications that fed this profile.

1 Media used

high

2 Optimum temperature for growth

low

42 °C

Low confidence · score 9.66 · 1 source

Evidence (6)
Other values reported (4)

3 Time required to grow

high

24-48 h

High confidence · score 18.23 · 7 sources

Evidence (6)
Other values reported (4)
Sources disagree: "24-48 h" (score 18.23) versus "1-6 h" (score 17.5). Both are shown; a reviewer should decide.

4 Colony morphology

low

The S. aureus L-form colonies showed typical 'fried-egg' morphology and the cells had deficient cell wall, showed morphological diversity, and stained Gram-negative.

Low confidence · score 2.1 · 1 source

Evidence (1)
Other values reported (4)
  • On solid agar media, staphylococcal SCVs are characterized by tiny colonies with deviant colony morphology. Low confidence · score 1.09 · 1 source
    Evidence (1)
  • Microbial isolates were identified through Gram staining, colony morphology, and biochemical tests (catalase, coagulase, oxidase). Low confidence · score 1.09 · 1 source
    Evidence (1)
  • Nasal swabs taken from them were inoculated onto Blood Agar & Mannitol Salt Agar within 1 hour and incubated aerobically at 37 °C for 24-48 hours. β-haemolytic colonies & Mannitol fermenting colonies which showed gram positive cocci in clusters in gram staining and produced Catalase & Coagulase were identified as S. aureus . Low confidence · score 1.05 · 1 source
    Evidence (1)
  • S. aureus appears as staphylococci (grape-like clusters) when viewed through a microscope, and has large, round, golden-yellow colonies, often with hemolysis, when grown on blood agar plates. Low confidence · score 0.98 · 1 source
    Evidence (1)
    • S. aureus appears as staphylococci (grape-like clusters) when viewed through a microscope, and has large, round, golden-yellow colonies, often with hemolysis, when grown on blood agar plates.Staphylococcus aureus — Wikipedia, 2026

5 Gram character

high

Gram-positive

High confidence · score 54.56 · 7 sources

Evidence (7)
Other values reported (1)
Sources disagree: "Gram-positive" (score 54.56) versus "Gram-negative" (score 42.64). Both are shown; a reviewer should decide.

6 Biochemical tests for identification

high

7 References used

81 sources
  1. MED:42228720 doi:10.1371/journal.pone.0336888 · via Europe PMC · supported: Gram, Biochemical tests
  2. MED:42119791 doi:10.1016/j.mimet.2026.107546 · via Europe PMC · supported: Media, Growth time
  3. MED:42078300 doi:10.7759/cureus.107998 · via Europe PMC · supported: Biochemical tests, Gram
  4. MED:42064530 doi:10.7759/cureus.106128 · via Europe PMC · supported: Biochemical tests, Media, Gram
  5. MED:42245445 doi:10.14202/vetworld.2026.1581-1594 · via Europe PMC · supported: Biochemical tests
  6. MED:42510048 doi:10.3390/diagnostics16142184 · via Europe PMC · supported: Gram
  7. MED:41853106 doi:10.1128/asmcr.00138-25 · via Europe PMC · supported: Biochemical tests, Media
  8. PPR:PPR1267853 doi:10.64898/2026.03.05.26347684 · via Europe PMC · supported: Colony, Biochemical tests
  9. MED:42273392 doi:10.2147/idr.s575283 · via Europe PMC · supported: Biochemical tests, Gram
  10. PPR:PPR1278961 doi:10.1099/acmi.0.001284.v1 · via Europe PMC · supported: Gram
  11. MED:42378733 doi:10.1016/j.diagmicrobio.2026.117535 · via Europe PMC · supported: Growth time
  12. MED:42230339 doi:10.3201/eid3206.260342 · via Europe PMC · supported: Gram
  13. MED:41848287 doi:10.1128/aem.02595-25 · via Europe PMC · supported: Growth time
  14. PPR:PPR1280156 · via bioRxiv / medRxiv (via Europe PMC) · supported: Biochemical tests, Media
  15. PPR:PPR1286330 · via bioRxiv / medRxiv (via Europe PMC) · supported: Biochemical tests
  16. PPR:PPR1291963 · via bioRxiv / medRxiv (via Europe PMC) · supported: Biochemical tests
  17. zenodo:18504666 · via Zenodo · supported: Biochemical tests
  18. wikipedia:118212 · via Wikipedia · supported: Gram, Biochemical tests, Media, Colony, Growth time
  19. MED:41241733 doi:10.1186/s12866-025-04404-7 · via Europe PMC · supported: Media, Biochemical tests, Temperature, Growth time
  20. MED:40777703 doi:10.7759/cureus.87503 · via Europe PMC · supported: Gram, Biochemical tests
  21. MED:40547784 doi:10.4103/jfmpc.jfmpc_1626_24 · via Europe PMC · supported: Gram
  22. PMID:40528537 · via PubMed (NCBI E-utilities) · supported: Media
  23. MED:41522923 doi:10.4103/jpbs.jpbs_1272_25 · via Europe PMC · supported: Gram
  24. 00034af344d24ef590b54527f567dbb1 · via DOAJ · supported: Gram
  25. 000f999c33f144f3bf49a3edea0584ac · via DOAJ · supported: Gram
  26. 00072b40db7d4ed9aed1206bcfe94737 · via DOAJ · supported: Gram
  27. doi:10.3934/microbiol.2025002 · via Crossref · supported: Media
  28. 00128dba874a4c969ee49ac5f9cbdef7 · via DOAJ · supported: Biochemical tests
  29. zenodo:13725212 · via Zenodo · supported: Gram, Biochemical tests, Media
  30. zenodo:11408805 · via Zenodo · supported: Growth time, Media
  31. zenodo:14592552 · via Zenodo · supported: Biochemical tests
  32. PMC10133824 · via PubMed Central (open access) · supported: Media, Growth time, Temperature
  33. PMID:37395643 · via PubMed (NCBI E-utilities) · supported: Gram, Growth time, Biochemical tests
  34. PMID:36671358 · via PubMed (NCBI E-utilities) · supported: Media, Growth time, Biochemical tests
  35. PMID:37760742 · via PubMed (NCBI E-utilities) · supported: Colony
  36. PMID:36226897 · via PubMed (NCBI E-utilities) · supported: Biochemical tests
  37. zenodo:11049040 · via Zenodo · supported: Biochemical tests
  38. zenodo:12789957 · via Zenodo · supported: Biochemical tests
  39. PMID:34357586 · via PubMed (NCBI E-utilities) · supported: Media, Biochemical tests
  40. PMID:36506149 · via PubMed (NCBI E-utilities) · supported: Gram
  41. PMID:35865434 · via PubMed (NCBI E-utilities) · supported: Growth time, Biochemical tests
  42. PMID:33397607 · via PubMed (NCBI E-utilities) · supported: Media
  43. PMID:33734646 · via PubMed (NCBI E-utilities) · supported: Media, Biochemical tests
  44. PMID:33571150 · via PubMed (NCBI E-utilities) · supported: Media, Biochemical tests
  45. 0007792d8c3b40258ba4f364ff1cffec · via DOAJ · supported: Gram
  46. PMID:34817325 · via PubMed (NCBI E-utilities) · supported: Growth time
  47. 000c06dc828f4c0db2b2ccfbff62358e · via DOAJ · supported: Growth time, Biochemical tests
  48. 00030c03e8ba48a3888c0f3ba43b7477 · via DOAJ · supported: Gram, Biochemical tests
  49. PMID:32926998 · via PubMed (NCBI E-utilities) · supported: Media
  50. PMID:30098850 · via PubMed (NCBI E-utilities) · supported: Temperature, Growth time
  51. PMID:31077143 · via PubMed (NCBI E-utilities) · supported: Gram
  52. 0011188b544a47b0b6ea981789f311c5 · via DOAJ · supported: Biochemical tests
  53. PMID:29845863 · via PubMed (NCBI E-utilities) · supported: Biochemical tests
  54. zenodo:8401427 · via Zenodo · supported: Media, Temperature, Growth time, Colony, Gram, Biochemical tests
  55. zenodo:3588099 · via Zenodo · supported: Media, Gram, Biochemical tests
  56. PMID:27071769 · via PubMed (NCBI E-utilities) · supported: Gram
  57. PMC4775967 · via PubMed Central (open access) · supported: Media
  58. PMID:25361600 · via PubMed (NCBI E-utilities) · supported: Temperature, Colony, Gram
  59. PMID:25250674 · via PubMed (NCBI E-utilities) · supported: Media
  60. PMID:24517232 · via PubMed (NCBI E-utilities) · supported: Media, Growth time
  61. PMID:24034418 · via PubMed (NCBI E-utilities) · supported: Gram
  62. https://openalex.org/W2162924609 · via OpenAlex · supported: Media, Growth time
  63. https://openalex.org/W2153844978 · via OpenAlex · supported: Growth time
  64. https://openalex.org/W2101610216 · via OpenAlex · supported: Gram, Colony, Biochemical tests
  65. 0012aafb151f486f92fc97f157f4a184 · via DOAJ · supported: Gram
  66. PMID:16597967 · via PubMed (NCBI E-utilities) · supported: Growth time
  67. https://openalex.org/W2128294325 · via OpenAlex · supported: Gram
  68. PMID:15472303 · via PubMed (NCBI E-utilities) · supported: Growth time
  69. PMID:10747148 · via PubMed (NCBI E-utilities) · supported: Growth time, Biochemical tests, Media
  70. PMID:10843049 · via PubMed (NCBI E-utilities) · supported: Biochemical tests
  71. PMID:10350393 · via PubMed (NCBI E-utilities) · supported: Media
  72. PMID:8706456 · via PubMed (NCBI E-utilities) · supported: Growth time
  73. PMID:7662517 · via PubMed (NCBI E-utilities) · supported: Media
  74. openaire · via OpenAIRE Explore · supported: Media, Growth time, Biochemical tests
  75. PMID:1582165 · via PubMed (NCBI E-utilities) · supported: Biochemical tests, Colony
  76. PMID:1796687 · via PubMed (NCBI E-utilities) · supported: Colony
  77. PMC249895 · via PubMed Central (open access) · supported: Biochemical tests
  78. PMID:14131367 · via PubMed (NCBI E-utilities) · supported: Biochemical tests, Media
  79. https://openalex.org/W2178682063 · via OpenAlex · supported: Temperature
  80. https://openalex.org/W2125676272 · via OpenAlex · supported: Media
  81. doi:10.58837/chula.the.2023.600 · via Crossref · supported: Biochemical tests, Gram

Catalogues to check by hand

These have no open interface, or their terms forbid automated querying. The app prepares the query; you open it.

Scan log — what each database returned
DatabaseStatusRecordsEvidenceTimeNote
NCBI Taxonomy — lineage and accepted name empty 0 0 1 ms TaxID 1280 (species).
LPSN — nomenclatural status skipped 0 0 0 ms Skipped — LPSN credentials not configured (free registration).
StrainInfo — strain cross-references empty 0 0 932 ms No response (endpoint may require a different path).
GBIF — name resolution empty 0 0 1 ms Matched as Staphylococcus aureus Rosenbach, 1884 (ACCEPTED).
Wikidata — identifier bridge empty 0 0 1 ms Item Q188121 matched.
DSMZ MediaDive — curated growth media empty 0 0 1 ms No media entries matched this name in MediaDive.
BacDive — curated strain phenotypes skipped 0 0 0 ms Skipped — BacDive credentials not configured. This is the single highest-value source; registration is free.
PubMed — culture and cultivation query hit 25 44 49 ms 25 abstracts retrieved (culture query).
PubMed — morphology and identification query hit 25 36 46 ms 25 abstracts retrieved (pheno query).
PubMed Central — open-access Methods sections hit 5 35 40 ms 5 open-access full texts mined.
Europe PMC — abstract search hit 25 53 49 ms 25 records from Europe PMC.
Europe PMC — full-text mining empty 0 0 3009 ms 0 full texts mined for Methods detail.
Crossref — DOI metadata hit 25 5 12 ms 25 DOI records (abstracts only where deposited).
OpenAlex — open scholarly graph hit 25 10 47 ms 25 works (inverted abstracts reconstructed locally).
Semantic Scholar — abstracts empty 0 0 535 ms Rate-limited or unavailable (keyless access is throttled).
DOAJ — open-access journals hit 20 23 25 ms 20 open-access articles.
OpenAIRE — repository publications hit 20 20 32 ms 20 repository publications.
SciELO — regional journals empty 0 0 1048 ms No parseable SciELO response (their JSON output is unstable; a deep link is still provided).
NCBI Bookshelf — reference texts hit 8 0 3 ms 8 reference-text chapters listed.
CORE — aggregated repositories skipped 0 0 0 ms Skipped — no API key configured.
Springer Nature — publisher metadata skipped 0 0 0 ms Skipped — no API key configured.
ScienceDirect — publisher metadata skipped 0 0 0 ms Skipped — no API key configured.
bioRxiv / medRxiv — preprints hit 12 8 18 ms 12 preprints (not peer reviewed — weighted down).
Zenodo — datasets and protocols hit 15 33 34 ms 15 deposits (datasets, theses, protocols).
Wikipedia — orientation only hit 1 27 12 ms Article retrieved (lowest weight).
ATCC — deep link empty 0 0 0 ms Deep link prepared — open manually.
NCTC / UKHSA — deep link empty 0 0 0 ms Deep link prepared — open manually.
Google Scholar — deep link (not crawled) empty 0 0 0 ms Deep link prepared — open manually.
protocols.io — deep link empty 0 0 0 ms Deep link prepared — open manually.
ResearchGate — deep link empty 0 0 0 ms Deep link prepared — open manually.